Francis Kim, MD | Associate Professor of Medicine
Dr. Kim has been involved in two main areas of
research, which are both funded by the NIH. The first involves the
effects of diabetes/obesity on vascular function and second involves the
use of hypothermia in cardiac arrest resuscitation. Dr. Kim's research focuses on studying endothelial nitric oxide
signaling and vascular inflammation. Further, his lab is interested in
examining the role of insulin resistance and obesity in the development
of vascular disease. Both cellular and molecular approaches are used
in cell culture and mouse models.
The Kim laboratory focuses on the
biology of endothelial nitric oxide signaling and the cellular
mechanisms by which nutrient excess (free fatty acids and glucose)
impair nitric oxide production. The second focus of the Kim lab centers
on examining cellular mechanisms which activate vascular inflammatory
pathways during nutritional excess.