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Kim Laboratory   

Francis Kim, MD | Associate Professor of Medicine

Dr. Kim has been involved in two main areas of research, which are both funded by the NIH. The first involves the effects of diabetes/obesity on vascular function and second involves the use of hypothermia in cardiac arrest resuscitation.  Dr. Kim's research focuses on studying endothelial nitric oxide signaling and vascular inflammation.  Further, his lab is interested in examining the role of insulin resistance and obesity in the development of vascular disease.  Both cellular and molecular approaches are used in cell culture and mouse models. 

The Kim laboratory focuses on the biology of endothelial nitric oxide signaling and the cellular mechanisms by which nutrient excess (free fatty acids and glucose) impair nitric oxide production. The second focus of the Kim lab centers on examining cellular mechanisms which activate vascular inflammatory pathways during nutritional excess.